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Vaccine Adjuvants
- Editore:
Humana Press Inc.
- Collana:
- Infectious Disease
- EAN:
9781617372407
- ISBN:
1617372404
- Pagine:
- 284
- Formato:
- Paperback
- Lingua:
- Inglese
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Descrizione Vaccine Adjuvants
A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.
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