Quantitative Drug Design

This volume teaches readers how to apply traditional ligand-based quantitative drug design methods, as a complement to recent 3D macromolecular structure-based methods. The text requires only a modest training in chemistry. Each subject is treated in enough detail that readers could apply the method to their own data. The book begins at an introductory level and builds from there. It includes a comprehensive integration of physical and computational chemistry, physical biochemistry, physical organic chemistry, and statistics at understandable levels.