Plasma free amino acids changes in HCC patients
- Editore:
LAP Lambert Academic Publishing
- EAN:
9783659847400
- ISBN:
3659847402
- Pagine:
- 120
- Formato:
- Paperback
- Lingua:
- Tedesco
Descrizione Plasma free amino acids changes in HCC patients
The aim of the book is to investigate plasma free amino acids profile as a possible diagnostic/prognostic factor in hepatocellular carcinoma patients. This study included 71 Hepatocellular cacinoma patients, and 30 chronic HCV patients in addition to 30 healthy controls. Laboratory investigations including; complete blood picture, liver function tests, serum alpha fetoprotein, hepatitis viral markers. The book showed a statistically significant increase of methionine, tyrosine, ornithine, citrulline, glycine, phenylalanine, alanine, glutamate, proline, and arginine and decrease of valine, aspartate, leucine/isoleucine, BTR and fischer ratio in hepatocellular carcinoma compared to control group. Also, it indicated that there was a statistically significant correlation between BTR and platelets, alanine transaminase, albumin, bilirubin and alpha fetoprotein and significant differences in BTR among Child-Pugh A, B and C. Our results suggested that the plasma free amino acids profile is considered valuable for diagnosis and nutritional care in cancer patients.Furthermore, BTR reflects the pathological liver background with a high degree of correlation to other liver functional markers.