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Partition Equilibrium And Lipophilicity Of Hydroxamic Acids
- Editore:
LAP Lambert Academic Publishing
- EAN:
9783659430350
- ISBN:
3659430358
- Pagine:
- 92
- Formato:
- Paperback
- Lingua:
- Tedesco
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Descrizione Partition Equilibrium And Lipophilicity Of Hydroxamic Acids
N-Arylhydroxamic acids are drug like molecules. Biological activity always depends upon physico-chemical property namely lipophilicity, which has direct impact on the potency of the molecule. Partition coefficient is a measure of how well a substance partitions between a lipid and water.The partition coefficient has a strong influence on ADME properties of molecules. Both of these parameters are important factor in QSAR.
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