Mechanisms underlying cannabis effects on the brain di Aitziber Mendiguren, Joseba Pineda edito da LAP Lambert Academic Publishing
Alta reperibilità

Mechanisms underlying cannabis effects on the brain

Modulation of monoaminergic systems by cannabinoids in the central nervous system

EAN:

9783659325250

ISBN:

3659325252

Pagine:
128
Formato:
Paperback
Lingua:
Tedesco
Acquistabile con o la

Descrizione Mechanisms underlying cannabis effects on the brain

Cannabinoid system regulates synaptic transmission in different brain regions. In this work, we study by electrophysiological techniques the effect of cannabinoids on the locus coeruleus (LC) and the dorsal raphe nucleus (DRN), the main noradrenergic and serotonergic nuclei in the central nervous system, respectively. These nuclei play a crucial role in the control of pain, mood,learning/memory, sleep-wake cycle, arousal and rewarding behavior. We demonstrate that cannabinoids alter the firing activity of LC cells and regulate glutamatergic system in this nucleus. We also describe how cannabinoids modulate GABAergic system in the DRN. In summary, our work shows that cannabinoids affect the neurons of the LC and DRN by a complex mechanism. The data of this study could explain why cannabis consumption results in a disruption of attention.

Spedizione gratuita
€ 56.88
o 3 rate da € 18.96 senza interessi con
Disponibile in 10-12 giorni
servizio Prenota Ritiri su libro Mechanisms underlying cannabis effects on the brain
Prenota e ritira
Scegli il punto di consegna e ritira quando vuoi

Recensioni degli utenti

e condividi la tua opinione con gli altri utenti