Lrrn2

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Leucine-rich repeat neuronal protein 2 is a protein that in humans is encoded by the LRRN2 gene.The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas.