Itga2b

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene.ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation.