Isolation of Cobra Venom Cytotoxin FVIb di Dalia Ali Gaber, Mohamed Farid El-Asmer, Kamelia Ahmed Zaki edito da LAP Lambert Academic Publishing
Alta reperibilità

Isolation of Cobra Venom Cytotoxin FVIb

Testing cytolysis on normal and malignant cells

EAN:

9783846582114

ISBN:

3846582115

Pagine:
148
Formato:
Paperback
Lingua:
Tedesco
Acquistabile con o la

Descrizione Isolation of Cobra Venom Cytotoxin FVIb

The search for cancer cure from natural products have been practiced for over a century. For the last 25 years, El-Asmer and co-workers were pursuing the search for potential therapeutic agent or new drug models from snake venoms. This work was presented for partial fulfillment of M.D. in Biochemistry. A cytolytic, non-antigenic, 8 kDa, glycoprotein (Fraction VIb) was isolated from crude Naja nigricollis nigricollis spitting cobra venom. This protein is stable at different pH values and different temperatures up to 100ºC, lethal to mice, with LD50 1.83 mg/kg. Small doses induced cytolytic effect on hepatocellular carcinoma, colon cancer and breast cancer cells while larger doses caused hemolysis of red blood cells. Thus, this protein can be considered a target compound for further researches as it can be a potential bio-therapeutic agent for cancer treatment, or a model for new drug design.

Spedizione gratuita
€ 61.22
o 3 rate da € 20.41 senza interessi con
Disponibile in 10-12 giorni
servizio Prenota Ritiri su libro Isolation of Cobra Venom Cytotoxin FVIb
Prenota e ritira
Scegli il punto di consegna e ritira quando vuoi

Recensioni degli utenti

e condividi la tua opinione con gli altri utenti