Ipcs Mode of Action Framework: Ipcs Harmonization Project Document

The use of structured frameworks in chemical risk assessment promotes transparent, harmonized approaches. This book presents two IPCS frameworks originally published in Critical Reviews in Toxicology, in a user-friendly large format. Part 1 contains the IPCS Framework for Analysing the Relevance of a Cancer Mode of Action for Humans, along with three case studies illustrating its application. Part 2 contains the IPCS Framework for Analysing the Relevance of a Non-Cancer Mode of Action for Humans.