Hypoxanthine-Guanine Phosphoribosyltransferase

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme that in humans is encoded by the HPRT1 gene.HGPRT is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate. This reaction transfers the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate to the purine.