Gonadal sex differentiation and development in Japanese tiger puffer

Brain type and ovarian type aromatase in Japanese tiger puffer (Takifugu rubripes) play important roles in gonadal sex differentiation and interact with factors related to this process. Again, inhibition of aromatase in vivo and in vitro results in alteration of the aromatase isoforms followed by imbalance in potential sex steroids and irreversible masculinization. This book describes the role of aromatase isoforms in Takifugu rubripes in relation to gonadal sex differentiation, gonadal development and compares the activity of the two isoforms present in brain and gonads in producing potential sex steroid E2 and also in regulating androgen-estrogen balance. Moreover, this book provides important information on the aromatase gene and its interactions with different factors related to sexuality of tiger puffer which can be helpful for studying different genetic and endocrine factors related to gonadal sex determination, differentiation and development of this fish.