Fbxw2
- Editore:
Betascript Publishing
- EAN:
9786136423654
- ISBN:
6136423650
- Pagine:
- 80
- Formato:
- Paperback
Descrizione Fbxw2
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. F-box/WD repeat-containing protein 2 is a protein that in humans is encoded by the FBXW2 gene.F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains.
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