Enzyme-Prodrug Strategies for Cancer Therapy edito da Springer US
Alta reperibilità

Enzyme-Prodrug Strategies for Cancer Therapy

Editore:

Springer US

EAN:

9780306458958

ISBN:

0306458950

Pagine:
276
Formato:
Hardback
Lingua:
Inglese
Acquistabile con o la

Descrizione Enzyme-Prodrug Strategies for Cancer Therapy

Antibody-directed enzyme prodrug therapy (ADEPT) directly addresses the major problem in cancer chemotherapy-its lack of selectivity. Antibody delivery combined with the amplification provided by the enzymatic activation of prodrugs enables selection to be made between tumour and normal tissue. ADEPT offers a novel field of opportunities in the therapy of systemic cancer and may be a major advance for the treatment of solid tumours. This book is the first to describe ADEPT in detail. Each chapter reviews an aspect of the immunology, enzymology, biochemistry, chemistry, and cancer chemotherapy which have been integrated into the ADEPT concept. An additional chapter describes the related approach of gene-directed enzyme prodrug therapy (GDEPT). This latter approach is still in its infancy but ADEPT has entered the clinic. The initial clinical studies with ADEPT are included and discussed in detail.

Spedizione gratuita
€ 224.22
o 3 rate da € 74.74 senza interessi con
Disponibile in 10-12 giorni
servizio Prenota Ritiri su libro Enzyme-Prodrug Strategies for Cancer Therapy
Prenota e ritira
Scegli il punto di consegna e ritira quando vuoi

Recensioni degli utenti

e condividi la tua opinione con gli altri utenti