Dusp3

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Dual specificity protein phosphatase 3 is an enzyme that in humans is encoded by the DUSP3 gene.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation.