Dusp12

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Dual specificity protein phosphatase 12 is an enzyme that in humans is encoded by the DUSP12 gene.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation.