Cytochrome P450

The Second Edition reviews the impressive progress that has been made in the last ten years in cytochrome P450 research. Chapters emphasize structure, mechanism, biochemistry, and regulation. This edition offers expanded coverage of P450 crystal structures, site-specific mutagenesis as a probe of structure and function. New chapters explore the hormonal regulation of P450 enzymes, the cytochrome P450-catalyzed oxidation of eicosanoids, human P450 enzymes, and thiolate-ligated hemoproteins other than P450.