Cnot7

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. CCR4-NOT transcription complex subunit 7 is a protein that in humans is encoded by the CNOT7 gene.The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.