Cd11c

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a human gene.This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.