Cbl (Gene)

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Cbl (named after Casitas B-lineage Lymphoma) is a mammalian gene encoding several proteins including E3 ubiquitin-protein ligase CBL involved in cell signalling and protein ubiquitination. Mutations to this gene have been implication in a number of human cancers, particularly acute myeloid leukaemia.