Cacng2

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Calcium channel, voltage-dependent, gamma subunit 2, also known as CACNG2 or stargazin is a protein which in humans is encoded by the CACNG2 gene.L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This protein is similar to the mouse stargazin protein, mutations in which have been associated with absence seizures, also known as petit-mal or spike-wave seizures. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family.