Btg1

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Protein BTG1 is a protein that in humans is encoded by the BTG1 gene.The BTG1 gene locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. It is a member of a family of antiproliferative genes. BTG1 expression is maximal in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. It negatively regulates cell proliferation.