Brwd2
- Editore:
Betascript Publishing
- EAN:
9786135209532
- ISBN:
6135209531
- Pagine:
- 76
- Formato:
- Paperback
Descrizione Brwd2
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Bromodomain and WD repeat-containing protein 2 is a protein that in humans is encoded by the BRWD2 gene.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
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