Beta Cells
Functions, Pathology & Research
- Editore:
Nova Science Publishers Inc
- Collana:
- Cell Biology Research Progress
- EAN:
9781617612121
- ISBN:
161761212X
- Pagine:
- 176
- Formato:
- Hardback
- Lingua:
- Inglese
Descrizione Beta Cells
Beta cells or ß-cells, are a type of cell in the pancreas in areas called the islets of Langerhans. They make up 65-80% of the cells in the islets. Pancreatic B-cell is the only cell type that produces insulin to regulate glucose metabolism in the body. The insufficiency of insulin-producing B-cells results in dysregulation of blood glucose control, termed as type 1 diabetes. This book presents current research from across the globe in the study of Beta-cells, including the induction of pancreatic cancer cell death by elevated concentrations of extracellular zinc; the role of Rab GTPases and their effectors in the insulin secretory pathway of the pancreatic beta cell; In vivo reprogramming of pancreatic A-cells into B-like cells; and the role of glucocortoids, exercise and glucolipotoxicity with regard to stress and pancreatic B-cell function.