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Apoptosis related proteins p53 and Bcl-2 in hepatocellular carcinoma
- Editore:
LAP Lambert Academic Publishing
- EAN:
9783659611117
- ISBN:
3659611115
- Pagine:
- 292
- Formato:
- Paperback
- Lingua:
- Tedesco
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Descrizione Apoptosis related proteins p53 and Bcl-2 in hepatocellular carcinoma
Hepatitis B virus and hepatitis C virus may be involved in hepatocarcinogenesis in patients with HCC. These viral infections may be responsible, at least in a part, for the mutational change in the p53 gene and may affect the expression of the Bcl-2 protein in HCC patients. p53 and Bcl-2 proteins overexpression was detected in serum and tissues in HCC patients positive for hepatitis B or C or both and this overexpression was more frequently associated with HBV infection than HCV infection.
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