Akt2

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. RAC-beta serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT2 gene.This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phosphorylating several known proteins.