Actr1a
- Editore:
Betascript Publishing
- EAN:
9786135109214
- ISBN:
6135109219
- Pagine:
- 128
- Formato:
- Paperback
Descrizione Actr1a
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Alpha-centractin is a protein that in humans is encoded by the ACTR1A gene.This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
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