Fragment-Based Drug Discovery and X-ray Crystallography

16Introduction to Fragment-Based Drug Discovery, by Daniel A. Erlanson Fragment Screening Using X-Ray Crystallography, by Thomas G. Davies and Ian J. TickleHsp90 Inhibitors and Drugs from Fragment and Virtual Screening, by Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey and Roderick E. HubbardCombining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors, by Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton, Corey Strickland, Johannes H. Voigt, Zhaoning Zhu and Andrew W. StamfordCombining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery, by Michael Hennig, Armin Ruf and Walter HuberTargeting Protein Protein Interactions and Fragment-Based Drug Discovery, by Eugene Valkov, Tim Sharpe, May Marsh, Sandra Greive and Marko HyvönenFragment Screening and HIV Therapeutics, by Joseph D. Bauman, Disha Patel and Eddy ArnoldFragment-Based Approaches and Computer-Aided Drug Discovery,16 by Didier Rognan04D. A. ErlansonIntroduction to Fragment-Based Drug DiscoveryT. G. DaviesIan J. TickleFragment Screening Using X-Ray CrystallographyS. RoughleyL. WrightP. BroughA. Massey R. E. HubbardHsp90 Inhibitors and Drugs from Fragment and Virtual ScreeningD. F. WyssY.-S. WangH. L. EatonC. StricklandJ.s H. VoigtZ. Zhu A. W. StamfordCombining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 InhibitorsM. HennigA. Ruf Walter HuberCombining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug DiscoveryE. ValkovT. SharpeM. MarshSa. Greive M. HyvönenTargeting Protein Protein Interactions and Fragment-Based Drug DiscoveryJ.h D. BaumanD. Patel E. ArnoldFragment Screening and HIV TherapeuticsD. RognanFragment-Based Approaches and Computer-Aided Drug Discovery